Computerized curve fitting in the analysis of hydrogen gas clearance curves.

@article{Livingston1989ComputerizedCF,
  title={Computerized curve fitting in the analysis of hydrogen gas clearance curves.},
  author={Edward H. Livingston and Terry Reedy and Felix W. Leung and Paul H. Guth},
  journal={The American journal of physiology},
  year={1989},
  volume={257 4 Pt 1},
  pages={G668-75}
}
Hydrogen gas clearance curves obtained from the rat gastric corpus were digitized into a computer and then analyzed by three methods: 1) linear regression of log-transformed data, 2) direct curve fitting with a modified Gauss-Newton nonlinear regression algorithm, and 3) Zierler's height-over-area algorithm. For linear regression of log-transformed data, if the initial base-line estimate was inaccurate or normal amounts of experimental noise were present, the log-transformed data was skewed… CONTINUE READING

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