Computerized continuous infusion of intravenous anesthetic drugs during pediatric cardiac surgery.

@article{Kern1991ComputerizedCI,
  title={Computerized continuous infusion of intravenous anesthetic drugs during pediatric cardiac surgery.},
  author={Frank H. Kern and Ross M. Ungerleider and Joseph R. Jacobs and Jeffrey L. Boyd and Joseph Gerald Reves and Daniel L. Goodman and William J. Greeley},
  journal={Anesthesia and analgesia},
  year={1991},
  volume={72 4},
  pages={
          487-92
        }
}
We evaluated the efficacy of a computer-assisted continuous infusion device (CACI) using a two-drug infusion of midazolam and sufentanil as an anesthetic technique during pediatric cardiac surgery. Seventeen pediatric patients were anesthetized with CACI using age-appropriate pharmacokinetic models for administering sufentanil and midazolam. Predicted CACI plasma concentrations were correlated with assayed plasma drug concentrations at eight predefined intervals. The accuracy was assessed using… CONTINUE READING
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