Computerized analysis of audible and ultrasonic vocalizations of rats as a standardized measure of pain-related behavior.

@article{Han2005ComputerizedAO,
  title={Computerized analysis of audible and ultrasonic vocalizations of rats as a standardized measure of pain-related behavior.},
  author={Jeong Seok Han and Gary C Bird and Weidong Li and Justina Jones and Volker Neugebauer},
  journal={Journal of neuroscience methods},
  year={2005},
  volume={141 2},
  pages={261-9}
}
The behavioral assessment of experimental pain is essential for the analysis of pain mechanisms and the validation of therapeutic targets. Arthritic pain, in particular, is significantly associated with negative affective states and disorders. Here we present a standardized method for the quantitative analysis of audible and ultrasonic (25 +/- 4 kHz) vocalizations in awake rats as a measure of higher integrated behavior in a model of arthritic pain. A bat detector and a condenser microphone… CONTINUE READING

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