Computer reconstruction of the spread of excitation in nerve terminals with inhomogeneous channel distribution

@article{Peres1986ComputerRO,
  title={Computer reconstruction of the spread of excitation in nerve terminals with inhomogeneous channel distribution},
  author={Asher Peres and Francesco Andrietti},
  journal={European Biophysics Journal},
  year={1986},
  volume={13},
  pages={235-243}
}
A direct numerical integration method, as modified by Du Fort and Frankel (1953), has been used to solve the partial differential equation system which describes the spread of action potential in a mammalian nerve terminal. Branching of the terminal as well as inhomogeneous distributions of Na+ and K+ voltage-dependent channels (Brigant and Mallart 1982) have been incorporated in the model. Using the channel densities and the kinetic parameters measured in the node of Ranvier, the… CONTINUE READING
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