Computer prediction of potential immunogenic determinants from protein amino acid sequence.

@article{Krchk1987ComputerPO,
  title={Computer prediction of potential immunogenic determinants from protein amino acid sequence.},
  author={Viktor Krchň{\'a}k and O. Mach and Alisha Maly},
  journal={Analytical biochemistry},
  year={1987},
  volume={165 1},
  pages={200-7}
}
In proteins, immunogenic determinants that can induce protein-reactive antipeptide antibodies reside mostly in those parts of the molecule that have a high tendency to form beta-turns. A program for an IBM personal computer which predicts protein immunogenic determinants is described. The program predicts potential immunogenic determinants from protein amino acid sequences according to a Chou-Fasman-based probability of a beta-turn occurrence, p greater than 1.5 X 10(-4)(P. Y. Chou and G. D… CONTINUE READING