With a newly developed computer analysis the space coordinates of light-reflecting points, attached to a subjects' face, were recorded across time with high temporal and spatial resolution. Under different experimental conditions the facial actions of 20 schizophrenics, 20 depressives and 20 normal controls were analysed. Furthermore, raters watched the synchronously recorded video versions of the subject's face and rated them as to expressivity. The findings indicate that depressive and schizophrenic patients exhibited reduced facial activity in the upper part of their face in social interaction conditions. Schizophrenic patients showed reduced facial action responsivity across different conditions and emotions. All patients were judged to be less expressive than normal controls by raters, suggesting apparent disintegrated elements in facial activity, although when computer-analysed they exhibited the same amount of facial activity.