Computer assisted design of a theophylline dosing regimen in acute bronchospasm: Serum concentrations and clinical outcome

@article{Verner1992ComputerAD,
  title={Computer assisted design of a theophylline dosing regimen in acute bronchospasm: Serum concentrations and clinical outcome},
  author={Dorte Verner and Hannah Seligmann and Simon Platt and Sebastian Dany and Shlomo Almog and L. Zulty and Hillel Halkin and Dr. D. Ezra},
  journal={European Journal of Clinical Pharmacology},
  year={1992},
  volume={43},
  pages={29-33}
}
The effect of intravenous theophylline on the outcome of inhospital treatment of acute bronchospasm has been assessed, comparing the results achieved by computer-assisted dosing, designed to achieve and maintain a serum theophylline level of 16 μg · ml−1 (10 patients) with those of unaided physicians (15 control patients). The outcome measures compared were clinical improvement, peak expiratory flow rate and serum theophylline concentration. Loading doses of theophylline in the control and… CONTINUE READING
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