A study was carried out to compare routine sialography and combination sialo-CT. The results in 36 patients with afflictions of the parotid and submandibular region are discussed. In addition to tumors, regarded as primary indications, inflammatory disorders were also considered. The diagnosis made by routine sialography is regularly confirmed by computed sialography (CTS), which is often an important complementary means. Visualization of the deep parotid lobe and parapharyngeal space (third plane) is very important for making the diagnosis and planning therapy.