Computational systems approach for drug target discovery.

  title={Computational systems approach for drug target discovery.},
  author={Nagasuma R. Chandra},
  journal={Expert opinion on drug discovery},
  volume={4 12},
IMPORTANCE OF THE FIELD The shift in focus from ligand based design approaches to target based discovery over the last two to three decades has been a major milestone in drug discovery research. Currently, it is witnessing another major paradigm shift by leaning towards the holistic systems based approaches rather the reductionist single molecule based methods. The effect of this new trend is likely to be felt strongly in terms of new strategies for therapeutic intervention, new targets… CONTINUE READING

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