Computational protein design.

@article{KraemerPecore2001ComputationalPD,
  title={Computational protein design.},
  author={Christina M Kraemer-Pecore and Andrew M Wollacott and John R. Desjarlais},
  journal={Current opinion in chemical biology},
  year={2001},
  volume={5 6},
  pages={
          690-5
        }
}
The field of computational protein design is reaching its adolescence. Protein design algorithms have been applied to design or engineer proteins that fold, fold faster, catalyze, catalyze faster, signal, and adopt preferred conformational states. Further developments of scoring functions, sampling strategies, and optimization methods will expand the range of applicability of computational protein design to larger and more varied systems, with greater incidence of success. Developments in this… CONTINUE READING

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