Computational prediction of N-linked glycosylation incorporating structural properties and patterns

@article{Chuang2012ComputationalPO,
  title={Computational prediction of N-linked glycosylation incorporating structural properties and patterns},
  author={Gwo-Yu Chuang and Jeffrey C. Boyington and M. Gordon Joyce and Jiang Zhu and Gary J. Nabel and Peter D. Kwong and Ivelin Georgiev},
  journal={Bioinformatics},
  year={2012},
  volume={28 17},
  pages={2249-55}
}
MOTIVATION N-linked glycosylation occurs predominantly at the N-X-T/S motif, where X is any amino acid except proline. Not all N-X-T/S sequons are glycosylated, and a number of web servers for predicting N-linked glycan occupancy using sequence and/or residue pattern information have been developed. None of the currently available servers, however, utilizes protein structural information for the prediction of N-glycan occupancy. RESULTS Here, we describe a novel classifier algorithm… CONTINUE READING

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