Computational modelling of placental amino acid transfer as an integrated system

  title={Computational modelling of placental amino acid transfer as an integrated system},
  author={Nuttanont Panitchob and K. L. Widdows and I. P. Crocker and E D Johnstone and C P Please and C P Sibley and Joanna Glazier and Richard M. Lewis and B G Sengers},
  booktitle={Biochimica et biophysica acta},
Placental amino acid transfer is essential for fetal development and its impairment is associated with poor fetal growth. Amino acid transfer is mediated by a broad array of specific plasma membrane transporters with overlapping substrate specificity. However, it is not fully understood how these different transporters work together to mediate net flux across the placenta. Therefore the aim of this study was to develop a new computational model to describe how human placental amino acid… CONTINUE READING
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