Computational discovery of human coding and non-coding transcripts with conserved splice sites


MOTIVATION Long non-coding RNAs (lncRNAs) resemble protein-coding mRNAs but do not encode proteins. Most lncRNAs are under lower sequence constraints than protein-coding genes and lack conserved secondary structures, making it hard to predict them computationally. RESULTS We introduce an approach to predict spliced lncRNAs in vertebrate genomes combining… (More)
DOI: 10.1093/bioinformatics/btr314
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