Computational discovery of human coding and non-coding transcripts with conserved splice sites

Abstract

MOTIVATION Long non-coding RNAs (lncRNAs) resemble protein-coding mRNAs but do not encode proteins. Most lncRNAs are under lower sequence constraints than protein-coding genes and lack conserved secondary structures, making it hard to predict them computationally. RESULTS We introduce an approach to predict spliced lncRNAs in vertebrate genomes combining… (More)
DOI: 10.1093/bioinformatics/btr314
View Slides

Topics

  • Presentations referencing similar topics