Computational design of drug candidates for influenza A virus subtype H1N1 by inhibiting the viral neuraminidase-1 enzyme USMAN SUMO FRIEND TAMBUNAN* ARLI ADITYA PARIKESIT YONANIKO DEPHINTO FEIMMY RUTH PRATIWI SIPAHUTAR

  • Published 2014


Received January 14, 2014 It is critical to seek potential alternative treatments for H1N1 infections by inhibiting neuraminidase-1 enzyme. One of the viable options for inhibiting the activity of neuraminidase-1 is peptide drug design. In order to increase peptide stability, cyclization is necessary to prevent its digestion by protease enzyme. Cyclization… (More)


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