Computational complexity of a problem in molecular structure prediction.

@article{Ngo1992ComputationalCO,
title={Computational complexity of a problem in molecular structure prediction.},
author={J. Thomas Ngo and Joe Marks},
journal={Protein engineering},
year={1992},
volume={5 4},
pages={313-21}
}

The computational task of protein structure prediction is believed to require exponential time, but previous arguments as to its intractability have taken into account only the size of a protein's conformational space. Such arguments do not rule out the possible existence of an algorithm, more selective than exhaustive search, that is efficient and exact. (An efficient algorithm is one that is guaranteed, for all possible inputs, to run in time bounded by a function polynomial in the problem… CONTINUE READING