Computational assembly of polymorphic amyloid fibrils reveals stable aggregates.

Abstract

Amyloid proteins aggregate into polymorphic fibrils that damage tissues of the brain, nerves, and heart. Experimental and computational studies have examined the structural basis and the nucleation of short fibrils, but the ability to predict and precisely quantify the stability of larger aggregates has remained elusive. We established a complete… (More)
DOI: 10.1016/j.bpj.2012.12.037

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Cite this paper

@article{Smaoui2013ComputationalAO, title={Computational assembly of polymorphic amyloid fibrils reveals stable aggregates.}, author={Mohamed Raef Smaoui and Fr{\'e}d{\'e}ric Poitevin and Marc Delarue and Patrice Koehl and Henri Orland and J{\'e}r{\^o}me Waldisp{\"{u}hl}, journal={Biophysical journal}, year={2013}, volume={104 3}, pages={683-93} }