Computational aspects of protein identification by mass spectrometry.

  title={Computational aspects of protein identification by mass spectrometry.},
  author={Robin Gras and M M{\"u}ller},
  journal={Current opinion in molecular therapeutics},
  volume={3 6},
Recent developments in proteomics and genomics provide huge quantities of data to analyze. Automatic interpretation of mass spectrometry data has become essential for high-throughput processes aiming to study complete proteomes. There exist two main sources of mass spectrometric data: peptide mass fingerprint and fragmentation spectra, both of which require specific bioinformatic algorithms. We present a survey of these algorithms and discuss the efficiency of the different approaches and the… CONTINUE READING

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