Computational approaches to the detection and analysis of sequences with intramolecular G-quadruplex forming potential.

Abstract

Sequences with the potential to form intramolecular G-quadruplexes (G4-structures) are found in highly nonrandom distributions in the genomes of diverse organisms. These sequences are associated with nucleic acid metabolic processes ranging from transcription and translation to recombination and telomere function. Here we review different computational… (More)
DOI: 10.1007/978-1-59745-363-9_3

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@article{Ryvkin2010ComputationalAT, title={Computational approaches to the detection and analysis of sequences with intramolecular G-quadruplex forming potential.}, author={Paul Ryvkin and Steve G. Hershman and L Wang and F Brad Johnson}, journal={Methods in molecular biology}, year={2010}, volume={608}, pages={39-50} }