Computational approaches to cellular rhythms

@article{Goldbeter2002ComputationalAT,
  title={Computational approaches to cellular rhythms},
  author={Albert Goldbeter},
  journal={Nature},
  year={2002},
  volume={420},
  pages={238-245}
}
Oscillations arise in genetic and metabolic networks as a result of various modes of cellular regulation. In view of the large number of variables involved and of the complexity of feedback processes that generate oscillations, mathematical models and numerical simulations are needed to fully grasp the molecular mechanisms and functions of biological rhythms. Models are also necessary to comprehend the transition from simple to complex oscillatory behaviour and to delineate the conditions under… CONTINUE READING
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