Computational approaches for analyzing the mechanics of atherosclerotic plaques: a review.

  title={Computational approaches for analyzing the mechanics of atherosclerotic plaques: a review.},
  author={Gerhard A Holzapfel and John J. E. Mulvihill and Eoghan M. Cunnane and Michael T Walsh},
  journal={Journal of biomechanics},
  volume={47 4},
Vulnerable and stable atherosclerotic plaques are heterogeneous living materials with peculiar mechanical behaviors depending on geometry, composition, loading and boundary conditions. Computational approaches have the potential to characterize the three-dimensional stress/strain distributions in patient-specific diseased arteries of different types and sclerotic morphologies and to estimate the risk of plaque rupture which is the main trigger of acute cardiovascular events. This review article… CONTINUE READING
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