Computational and experimental analysis reveals a requirement for eosinophil-derived IL-13 for the development of allergic airway responses in C57BL/6 mice.

Abstract

Eosinophils are found in the lungs of humans with allergic asthma, as well as in the lungs of animals in models of this disease. Increasing evidence suggests that these cells are integral to the development of allergic asthma in C57BL/6 mice. However, the specific function of eosinophils that is required for this event is not known. In this study, we… (More)
DOI: 10.4049/jimmunol.1001148

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@article{Walsh2011ComputationalAE, title={Computational and experimental analysis reveals a requirement for eosinophil-derived IL-13 for the development of allergic airway responses in C57BL/6 mice.}, author={Elizabeth Rose Walsh and Juilee Thakar and Kindra Stokes and Fei Huang and R{\'e}ka Albert and Avery August}, journal={Journal of immunology}, year={2011}, volume={186 5}, pages={2936-49} }