Computational Validation of the Importance of Absolute Stereochemistry in Virtual Screening


Consideration of stereochemistry early in the identification and optimization of lead compounds can improve the efficiency and efficacy of the drug discovery process and reduce the time spent on subsequent drug development. These improvements can result by focusing on specific enantiomers that have the desired potential therapeutic effect (eutomers), while… (More)
DOI: 10.1021/ci700358r


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