Computational Strategies for a System-Level Understanding of Metabolism

  title={Computational Strategies for a System-Level Understanding of Metabolism},
  author={Paolo Cazzaniga and Chiara Damiani and Daniela Besozzi and Riccardo Colombo and Marco S. Nobile and Daniela Gaglio and Dario Pescini and Sara Molinari and Giancarlo Mauri and Lilia Alberghina and Marco Vanoni},
Cell metabolism is the biochemical machinery that provides energy and building blocks to sustain life. Understanding its fine regulation is of pivotal relevance in several fields, from metabolic engineering applications to the treatment of metabolic disorders and cancer. Sophisticated computational approaches are needed to unravel the complexity of metabolism. To this aim, a plethora of methods have been developed, yet it is generally hard to identify which computational strategy is most suited… CONTINUE READING
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