Computational Psychiatry of ADHD: Neural Gain Impairments across Marrian Levels of Analysis

@article{Hauser2016ComputationalPO,
  title={Computational Psychiatry of ADHD: Neural Gain Impairments across Marrian Levels of Analysis},
  author={Tobias U. Hauser and Vincenzo G. Fiore and Michael Moutoussis and Raymond J. Dolan},
  journal={Trends in Neurosciences},
  year={2016},
  volume={39},
  pages={63-73}
}
Attention-deficit hyperactivity disorder (ADHD), one of the most common psychiatric disorders, is characterised by unstable response patterns across multiple cognitive domains. However, the neural mechanisms that explain these characteristic features remain unclear. Using a computational multilevel approach, we propose that ADHD is caused by impaired gain modulation in systems that generate this phenotypic increased behavioural variability. Using Marr's three levels of analysis as a heuristic… CONTINUE READING
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