Bre1a, a histone H2B ubiquitin ligase, regulates the cell cycle and differentiation of neural precursor cells.
- Yugo Ishino, Yoshitaka Hayashi, +9 authors Seiji Hitoshi
- The Journal of neuroscience : the official…
- 2014
1 Excerpt
Computational Identification and Experimental Validation of MicroRNAs Binding to the Fragile X Syndrome Gene Fmr1
- Published 2014 in Neurochemical Research
Abstract
MicroRNAs (miRNAs) usually bind to their target mRNAs through imperfect base pairing in the 3′-untranslated regions (3′ UTRs) and regulate target gene expression via post-transcriptional suppression. In recent years, computational approaches to predict miRNA targets have facilitated the identification of potential target sites. In this study, we used three… (More)