Computation of Median Gene Clusters

  title={Computation of Median Gene Clusters},
  author={Sebastian B{\"o}cker and Katharina Jahn and Julia Mixtacki and Jens Stoye},
  journal={Journal of computational biology : a journal of computational molecular cell biology},
  volume={16 8},
Whole genome comparison based on gene order has become a popular approach in comparative genomics. An important task in this field is the detection of gene clusters, i.e., sets of genes that occur co-localized in several genomes. For most applications, it is preferable to extend this definition to allow for small deviations in the gene content of the cluster occurrences. However, relaxing the equality constraint increases the computational complexity of gene cluster detection drastically… CONTINUE READING

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