Comprehensive two-dimensional high-performance liquid chromatography system with immobilized liposome chromatography column and reversed-phase column for separation of complex traditional Chinese medicine Longdan Xiegan Decoction

  • Yun Wanga, Liang Kongd, +4 authors Zhengtao Wanga
  • Published 2009

Abstract

A comprehensive two-dimensional HPLC system with an immobilized liposome chromatography (ILC) column in conjunction with an RP column (in tandem) was developed for the screening and analysis of the membrane-permeable compounds in a traditional Chinese medicine prescription Longdan Xiegan Decoction (LXD). More than 50 components in LXDwere resolved using the developed separation system. Eight flavonoids and two iridoids were identified interacting with the ILC column; a system that mimics chromatography

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Cite this paper

@inproceedings{Wanga2009ComprehensiveTH, title={Comprehensive two-dimensional high-performance liquid chromatography system with immobilized liposome chromatography column and reversed-phase column for separation of complex traditional Chinese medicine Longdan Xiegan Decoction}, author={Yun Wanga and Liang Kongd and Xiaoyuan Leib and Lianghai Hub and Hanfa Zoub and Annie Blighe and Zhengtao Wanga}, year={2009} }