Comprehensive survey and geometric classification of base triples in RNA structures

Abstract

Base triples are recurrent clusters of three RNA nucleobases interacting edge-to-edge by hydrogen bonding. We find that the central base in almost all triples forms base pairs with the other two bases of the triple, providing a natural way to geometrically classify base triples. Given 12 geometric base pair families defined by the Leontis-Westhof… (More)
DOI: 10.1093/nar/gkr810

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