Comprehensive study of proteasome inhibitors against Plasmodium falciparum laboratory strains and field isolates from Gabon

@article{Kreidenweiss2008ComprehensiveSO,
  title={Comprehensive study of proteasome inhibitors against Plasmodium falciparum laboratory strains and field isolates from Gabon},
  author={Andrea Kreidenweiss and Peter Gottfried Kremsner and Benjamin Mordm{\"u}ller},
  journal={Malaria Journal},
  year={2008},
  volume={7},
  pages={187 - 187}
}
The emergence and spread of Plasmodium falciparum resistance to almost all available antimalarial drugs necessitates the search for new chemotherapeutic compounds. The ubiquitin/proteasome system plays a major role in overall protein turnover, especially in fast dividing eukaryotic cells including plasmodia. Previous studies show that the 20S proteasome is… CONTINUE READING