Comprehensive proteomic analysis of human cervical-vaginal fluid.

  title={Comprehensive proteomic analysis of human cervical-vaginal fluid.},
  author={Surendra Dasari and L Pereira and A. Pratapa Reddy and John-Edward A Michaels and Xinfang Lu and Thomas Jacob and Archana Thomas and Matthew J Rodland and Charles Roberts and Michael G. Gravett and Srinivasa R. Nagalla},
  journal={Journal of proteome research},
  volume={6 4},
Cervical-vaginal fluid (CVF) is a potential rich source of biomarkers for enhancing our understanding of human parturition and pathologic conditions affecting pregnancy. In this study, we performed a comprehensive survey of the CVF proteome in pregnancy utilizing multidimensional liquid chromatography (2D-LC) coupled with mass spectrometry and gel-electrophoresis-based protein separation and identification. In total, 150 unique proteins were identified using multiple protein identification… CONTINUE READING

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