Comprehensive pharmacokinetic model of insulin Glargine and other insulin formulations

@article{Tarn2005ComprehensivePM,
  title={Comprehensive pharmacokinetic model of insulin Glargine and other insulin formulations},
  author={Cristina Tar{\'i}n and Edgar Teufel and Jes{\'u}s Pic{\'o} and Jorge Bondia and Hans-J{\"o}rg Pfleiderer},
  journal={IEEE Transactions on Biomedical Engineering},
  year={2005},
  volume={52},
  pages={1994-2005}
}
In this paper, a comprehensive pharmacokinetic model for different insulin formulations including insulin Glargine is developed based on the model proposed by Trajanoski et al. (1993). Current models show limitations for insulin Glargine due to the appearance of an uncharacteristic peak in the concentration-time evolution of plasma insulin that does not… CONTINUE READING

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