Comprehensive mapping of post-translational modifications on synaptic, nuclear, and histone proteins in the adult mouse brain.

@article{TweedieCullen2009ComprehensiveMO,
  title={Comprehensive mapping of post-translational modifications on synaptic, nuclear, and histone proteins in the adult mouse brain.},
  author={Ry Yves Tweedie-Cullen and Johannes M Reck and Isabelle M Mansuy},
  journal={Journal of proteome research},
  year={2009},
  volume={8 11},
  pages={4966-82}
}
Post-translational modifications (PTMs) of proteins in the adult brain are known to mark activity-dependent processes for complex brain functions such as learning and memory. Multiple PTMs occur in nerve cells, and are able to modulate proteins in different subcellular compartments. In synaptic terminals, protein phosphorylation is the primary PTM that contributes to the control of the activity and localization of synaptic proteins. In the nucleus, it can modulate histones and proteins involved… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 59 extracted citations

Comprehensive Catalog of Currently Documented Histone Modifications.

Cold Spring Harbor perspectives in biology • 2015
View 15 Excerpts
Highly Influenced

Tyrosine phosphorylation switching of a G protein.

The Journal of biological chemistry • 2018

References

Publications referenced by this paper.
Showing 1-10 of 57 references

Similar Papers

Loading similar papers…