Comprehensive investigation of the presence of JC virus in AIDS patients with and without progressive multifocal leukoencephalopathy.

@article{Ferrante1997ComprehensiveIO,
  title={Comprehensive investigation of the presence of JC virus in AIDS patients with and without progressive multifocal leukoencephalopathy.},
  author={Pasquale Ferrante and Rita Caldarelli-Stefano and Elisabetta Omodeo-Zorini and Anna Elisabetta Cagni and Laura Cocchi and Fredy Suter and Renato Maserati},
  journal={Journal of medical virology},
  year={1997},
  volume={52 3},
  pages={235-42}
}
Progressive multifocal leukoencephalopathy (PML), a viral-induced demyelinating disease, is becoming relatively common, while many diagnostic and pathogenetic aspects remain to be clarified. A study was therefore undertaken in 64 AIDS patients suffering from various neurological disorders, including PML (12 subjects), with the specific objective of searching for JC virus (JCV) DNA by nested PCR (n-PCR) in cerebrospinal fluid (CSF), peripheral blood mononuclear cells (PBMCs), and urine collected… CONTINUE READING

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