Comprehensive investigation of oncogenic driver mutations in Chinese non-small cell lung cancer patients.

@article{Wang2015ComprehensiveIO,
  title={Comprehensive investigation of oncogenic driver mutations in Chinese non-small cell lung cancer patients.},
  author={Ruobing Wang and Yang Zhang and Yunjian Pan and Yangyang Li and Haichuan Hu and Deng Cai and Huan Li and Ting Ye and Xiaoyang Luo and Yiliang Zhang and Bin Li and Lei Shen and Yihua Sun and Haiquan Chen},
  journal={Oncotarget},
  year={2015},
  volume={6 33},
  pages={34300-8}
}
PURPOSE To determine the frequency of driver mutations in Chinese non-small cell lung cancer (NSCLC) patients. METHODS Comprehensive mutational analysis was performed in 1356 lung adenocarcinoma, 503 squamous cell carcinoma, 57 adenosquamous lung carcinoma, 19 large cell carcinoma and 8 sarcomatoid carcinoma. The effect of EGFR tyrosine kinase inhibitors (TKIs) on EGFR-mutated lung adenocarcinoma patients after disease recurrence was investigated. RESULTS Mutations in EGFR kinase domain… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 18 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 21 references

Similar Papers

Loading similar papers…