Comprehensive genome sequence analysis of a breast cancer amplicon.

@article{Collins2001ComprehensiveGS,
  title={Comprehensive genome sequence analysis of a breast cancer amplicon.},
  author={Colin Collins and Stanislav Volik and David Kowbel and David Ginzinger and Bauke Ylstra and Timothy Cloutier and Trevor K. Hawkins and Paul F. Predki and C{\'e}sar Gavil{\'a}n Mart{\'i}n and Meredith Wernick and Wen Lin Kuo and Alan R. Alberts and Joe W. Gray},
  journal={Genome research},
  year={2001},
  volume={11 6},
  pages={
          1034-42
        }
}
Gene amplification occurs in most solid tumors and is associated with poor prognosis. Amplification of 20q13.2 is common to several tumor types including breast cancer. The 1 Mb of sequence spanning the 20q13.2 breast cancer amplicon is one of the most exhaustively studied segments of the human genome. These studies have included amplicon mapping by comparative genomic hybridization (CGH), fluorescent in-situ hybridization (FISH), array-CGH, quantitative microsatellite analysis (QUMA), and… CONTINUE READING

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