Comprehensive determination of the cyclic FEE peptide chemical stability in solution.

Abstract

The FEE cyclic hexapeptide (cFEE) is an investigational new drug added to the insemination medium in order to improve the in vitro fertilization rate. The pharmacological activity of small peptides is highly dependent on the conservation of the amino acid sequence and of the structural conformation of the active site. To enhance the scientific knowledge… (More)
DOI: 10.1016/j.jpba.2013.10.026

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Cite this paper

@article{Rotival2014ComprehensiveDO, title={Comprehensive determination of the cyclic FEE peptide chemical stability in solution.}, author={Romain Rotival and M{\'e}lisande Bernard and Th{\'e}o Henriet and Martine Fourgeaud and J R Fabr{\'e}guettes and Elodie Surget and François Guyon and Bernard W Do}, journal={Journal of pharmaceutical and biomedical analysis}, year={2014}, volume={89}, pages={50-5} }