Comprehensive detection of human terminal oligo-pyrimidine (TOP) genes and analysis of their characteristics

@inproceedings{Yamashita2008ComprehensiveDO,
  title={Comprehensive detection of human terminal oligo-pyrimidine (TOP) genes and analysis of their characteristics},
  author={Riu Yamashita and Yutaka Suzuki and Nono Takeuchi and Hiroyuki Wakaguri and Takuya Ueda and Sumio Sugano and Kenta Nakai},
  booktitle={Nucleic acids research},
  year={2008}
}
Although the knowledge accumulated on the transcriptional regulations of eukaryotes is significant, the knowledge on their translational regulations remains limited. Thus, we performed a comprehensive detection of terminal oligo-pyrimidine (TOP), which is one of the well-characterized cis-regulatory motifs for translational controls located immediately downstream of the transcriptional start sites of mRNAs. Utilizing our precise 5'-end information of the full-length cDNAs, we could screen 1645… CONTINUE READING

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