Comprehensive biophysical model of the lac operon

  title={Comprehensive biophysical model of the lac operon},
  author={Kate Patterson and Tom{\'a}s Gedeon},
We introduce and analyze a detailed biophysical model of the control of the lac operon. The model connects two spatial scales: the biophysical parameters of molecular interactions at a molecular scale and the resulting expression level of lac genes measured on the cellular level. We parameterize the model to the extent possible and find parameter bounds for… CONTINUE READING