Comprehensive behavioral analysis of pituitary adenylate cyclase-activating polypeptide (PACAP) knockout mice

@inproceedings{Hattori2012ComprehensiveBA,
  title={Comprehensive behavioral analysis of pituitary adenylate cyclase-activating polypeptide (PACAP) knockout mice},
  author={Satoko Hattori and Keizo Takao and Koichi Tanda and Keiko Toyama and Norihito Shintani and Akemichi Baba and Hitoshi Hashimoto and Tsuyoshi Miyakawa},
  booktitle={Front. Behav. Neurosci.},
  year={2012}
}
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a neuropeptide acting as a neurotransmitter, neuromodulator, or neurotrophic factor. PACAP is widely expressed throughout the brain and exerts its functions through the PACAP-specific receptor (PAC(1)). Recent studies reveal that genetic variants of the PACAP and PAC(1) genes are associated with mental disorders, and several behavioral abnormalities of PACAP knockout (KO) mice are reported. However, an insufficient number of… CONTINUE READING

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