Comprehensive approach to structural and functional glycomics based on chemoselective glycoblotting and sequential tag conversion.

Abstract

Changes in protein glycosylation profoundly affect protein function. To understand these effects of altered protein glycosylation, we urgently need high-throughput technologies to analyze glycan expression and glycan-protein interactions. Methods are not available for amplification of glycans; therefore, highly efficient sample preparation is a major issue… (More)
DOI: 10.1021/ac702124d

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