Comprehensive analysis of protein-protein interactions between Arabidopsis MAPKs and MAPK kinases helps define potential MAPK signalling modules.

@article{Lee2008ComprehensiveAO,
  title={Comprehensive analysis of protein-protein interactions between Arabidopsis MAPKs and MAPK kinases helps define potential MAPK signalling modules.},
  author={Jin Suk Lee and Kyung Won Huh and Apurva Bhargava and Brian E. Ellis},
  journal={Plant signaling & behavior},
  year={2008},
  volume={3 12},
  pages={1037-41}
}
The Arabidopsis genome encodes a 20-member gene family of mitogen-activated protein kinases (MPKs) but biological roles have only been identified for a small subset of these crucial signalling components. In particular, it is unclear how the MPKs may be organized into functional modules within the cell. To gain insight into their potential relationships, we used the yeast two-hybrid system to conduct a directed protein-protein interaction screen between all the Arabidopsis MPKs and their… CONTINUE READING

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