Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues

@article{Murakami2006ComprehensiveAO,
  title={Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues},
  author={Yoshiki Murakami and Tatsuji Yasuda and Kenichi Saigo and Tetsuro Urashima and Hidenao Toyoda and Takeshi Okanoue and Kunitada Shimotohno},
  journal={Oncogene},
  year={2006},
  volume={25},
  pages={2537-2545}
}
MicroRNAs (miRNAs) are a non-coding family of genes involved in post-transcriptional gene regulation. These transcripts are associated with cell proliferation, cell differentiation, cell death and carcinogenesis. We analysed the miRNA expression profiles in 25 pairs of hepatocellular carcinoma (HCC) and adjacent non-tumorous tissue (NT) and nine additional chronic hepatitis (CH) specimens using a human miRNA microarray. Targets and references samples were co-hybridized to a microarray… CONTINUE READING
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