Comprehensive analysis of gene expression profiles provides insight into the pathogenesis of Crohn's disease

@inproceedings{Bo2018ComprehensiveAO,
  title={Comprehensive analysis of gene expression profiles provides insight into the pathogenesis of Crohn's disease},
  author={Lumin Bo and Hongyu Fu and Junchi Yang},
  booktitle={Molecular medicine reports},
  year={2018}
}
Crohn's disease (CD) is a type of inflammatory bowel disease that cannot be fully cured by medication or surgery. In the present study, the aim was to understand the underlying mechanisms of CD. Two CD microarray datasets were downloaded from The Gene Expression Omnibus database: GSE36807 (13 CD and 7 normal samples) and GSE59071 (8 CD and 11 normal samples). A series of bioinformatics analyses were conducted, including weighted gene co‑expression network analysis to identify stable modules… CONTINUE READING

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