Comprehensive aligned sequence construction for automated design of effective probes (CASCADE-P) using 16S rDNA

@article{DeSantis2003ComprehensiveAS,
  title={Comprehensive aligned sequence construction for automated design of effective probes (CASCADE-P) using 16S rDNA},
  author={T. Z. DeSantis and I. Dubosarskiy and S. R. Murray and Gary L. Andersen},
  journal={Bioinformatics},
  year={2003},
  volume={19 12},
  pages={1461-8}
}
MOTIVATION Prokaryotic organisms have been identified utilizing the sequence variation of the 16S rRNA gene. Variations steer the design of DNA probes for the detection of taxonomic groups or specific organisms. The long-term goal of our project is to create probe arrays capable of identifying 16S rDNA sequences in unknown samples. This necessitated the… CONTINUE READING