Comprehensive Survey of miRNA-mRNA Interactions Reveals That Ccr7 and Cd247 (CD3 zeta) are Posttranscriptionally Controlled in Pancreas Infiltrating T Lymphocytes of Non-Obese Diabetic (NOD) Mice

@inproceedings{Fornari2015ComprehensiveSO,
  title={Comprehensive Survey of miRNA-mRNA Interactions Reveals That Ccr7 and Cd247 (CD3 zeta) are Posttranscriptionally Controlled in Pancreas Infiltrating T Lymphocytes of Non-Obese Diabetic (NOD) Mice},
  author={Tha{\'i}s A. Fornari and Paula Barbim Donate and Amanda Freire Assis and Cl{\'a}udia Leal Macedo and Elza Tiemi Sakamoto-Hojo and Eduardo Ant{\^o}nio Donadi and Geraldo A Passos and Francesco Dotta},
  booktitle={PloS one},
  year={2015}
}
In autoimmune type 1 diabetes mellitus (T1D), auto-reactive clones of CD4+ and CD8+ T lymphocytes in the periphery evolve into pancreas-infiltrating T lymphocytes (PILs), which destroy insulin-producing beta-cells through inflammatory insulitis. Previously, we demonstrated that, during the development of T1D in non-obese diabetic (NOD) mice, a set of immune… CONTINUE READING