Comprehensive Mitochondrial Haplogroup Analysis System Based on Suspension-Array Technology Using DNA from Formalin-Fixed Paraffin-Embedded Autopsy Tissues (P07.214)

@article{Nishigaki2012ComprehensiveMH,
  title={Comprehensive Mitochondrial Haplogroup Analysis System Based on Suspension-Array Technology Using DNA from Formalin-Fixed Paraffin-Embedded Autopsy Tissues (P07.214)},
  author={Y. Nishigaki and Hiroko Hosoya and Makiko Naka-Mieno and T. Arai and M. Sawabe and M. Tanaka},
  journal={Neurology},
  year={2012},
  volume={78}
}
  • Y. Nishigaki, Hiroko Hosoya, +3 authors M. Tanaka
  • Published 2012
  • Biology
  • Neurology
  • Objective: To establish a suspension array-based analysis system for determining mitochondrial haplogroups, using DNA purified from formalin-fixed paraffin-embedded (FFPE) autopsy tissues. Background Because the evolutionary rate of mitochondrial DNA (mtDNA) is much higher than that of nuclear DNA, and because mtDNA is highly polymorphic, mitochondrial single nucleotide polymorphisms (mtSNPs) are expected to contribute more extensively to the functional differences among individuals than those… CONTINUE READING