Comprehensive Identification of Protein Substrates of the Dot/Icm Type IV Transporter of Legionella pneumophila

@inproceedings{Zhu2011ComprehensiveIO,
  title={Comprehensive Identification of Protein Substrates of the Dot/Icm Type IV Transporter of Legionella pneumophila},
  author={Wenhan Zhu and Simran Banga and Yunhao Tan and Cheng Zheng and Robert M. Stephenson and Jonathan M Gately and Zhao-Qing Luo},
  booktitle={PloS one},
  year={2011}
}
A large number of proteins transferred by the Legionella pneumophila Dot/Icm system have been identified by various strategies. With no exceptions, these strategies are based on one or more characteristics associated with the tested proteins. Given the high level of diversity exhibited by the identified proteins, it is possible that some substrates have been missed in these screenings. In this study, we took a systematic method to survey the L. pneumophila genome by testing hypothetical orfs… CONTINUE READING

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Molecular pathogenesis of infections caused by Legionella pneumophila

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