Comprehensive DNA recognition through concerted interactions from adjacent zinc fingers.

Abstract

Zinc fingers are small DNA-binding modules noted for their occurrence in a large number of eukaryotic transcription factors, and their use in protein engineering. Although it was expected that zinc fingers can bind to a wide diversity of DNA sequences, previous studies using model zinc finger domains from Zif268 (and Sp1) have revealed a potential… (More)

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@article{Isalan1998ComprehensiveDR, title={Comprehensive DNA recognition through concerted interactions from adjacent zinc fingers.}, author={Mark Isalan and A. Klug and Young Min Choo}, journal={Biochemistry}, year={1998}, volume={37 35}, pages={12026-33} }