Comprehensive Analysis of Silencing Mutants Reveals Complex Regulation of the Arabidopsis Methylome

@article{Stroud2013ComprehensiveAO,
  title={Comprehensive Analysis of Silencing Mutants Reveals Complex Regulation of the Arabidopsis Methylome},
  author={Hume Stroud and Maxim V. C. Greenberg and Suhua Feng and Yana V. Bernatavichute and Steven E. Jacobsen},
  journal={Cell},
  year={2013},
  volume={152},
  pages={352-364}
}
Cytosine methylation is involved in various biological processes such as silencing of transposable elements (TEs) and imprinting. Multiple pathways regulate DNA methylation in different sequence contexts, but the factors that regulate DNA methylation at a given site in the genome largely remain unknown. Here we have surveyed the methylomes of a comprehensive list of 86 Arabidopsis gene silencing mutants by generating single-nucleotide resolution maps of DNA methylation. We find that DNA… CONTINUE READING
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