Comprehensive Analysis of Long Non-Coding RNAs in Ovarian Cancer Reveals Global Patterns and Targeted DNA Amplification

@inproceedings{Akrami2013ComprehensiveAO,
  title={Comprehensive Analysis of Long Non-Coding RNAs in Ovarian Cancer Reveals Global Patterns and Targeted DNA Amplification},
  author={Rozita Akrami and Anders Jacobsen and Jessica I. Hoell and Nikolaus Schultz and Chris Sander and Erik Larsson},
  booktitle={PloS one},
  year={2013}
}
Long non-coding RNAs (lncRNAs) are emerging as potent regulators of cell physiology, and recent studies highlight their role in tumor development. However, while established protein-coding oncogenes and tumor suppressors often display striking patterns of focal DNA copy-number alteration in tumors, similar evidence is largely lacking for lncRNAs. Here, we… CONTINUE READING